What is it about psychedelics that has the power to change lives for the better? The answer might lie in the unique ways that psychedelics interact with the brain.

Depression. Anxiety. Addiction. Most everyone of us knows somebody who is battling such a condition. Talk therapies may help, but sometimes they don’t. Antidepressants may help, but sometimes they don’t. Some patients are of the opinion that antidepressants are like “Band-Aids” in the way that they never really tackle the underlying issues of their problems.

The incredible mainstream press microdosing has received has managed to avoid many discussions.

MDMA-assisted psychotherapy gave me the ability to feel compassion and empathy for myself.

Holotropic Breathwork is not just a breath technique. It was conceived as a non-drug way of accessing non-ordinary states of consciousness.

There is an urgent need for cultural humility in psychedelic science in order to prevent it from falling into the same limiting, and often unethical, traps that we see in Western science and medicine.

Cluster headaches to me feel like someone has my eyeball in their fist, steadily putting more and more pressure on it until it threatens to pop like a grape.

I chose to learn Grof’s methods for working therapeutically with LSD and use them in my private life to systematically explore my own mind and the mind of the universe as deeply as possible—73 high-dose sessions over 20 years.

There’s a beauty and sense of wonder that comes from knowing how the world works, and the nature of the psychedelic experience dovetails almost perfectly with that awareness.

First, the entire premise—that Schedule I status is the primary obstacle to research—is flat-out wrong.

Instead of worrying so much about addiction, which tends to correct itself when life becomes tolerable, maybe we should worry more about the sources of emotional suffering.

It’s been 50 years since the last one. The original idea was to hold followups every 10 years. But the war on drugs came along, and they were never held. It’s time to take another look at the current state of the art.

Should these drugs become part of medicine cabinets from San Francisco to America’s heartland, it will be high time to develop drug tests that control for the cultural diversity of this country’s doctors and patients.

Let’s go forward in time through the government’s ban on psychedelics, and look how it has blossomed into the psychedelic renaissance.

Psychotherapy-assisted psychedelic experiences may revolutionize how we treat mental illness. The philosophy and techniques have evolved over the past 50 years.

Part 3 | Dose #3 was the most intense, powerful, horrendous, terrifying, awful experience of my life. In the end, it was all worth it.

Part 2 | This time my dose was 45 mg of pure psilocybin. I took it and waited for the show to begin. There was fear and a sincere hope that this experience would not be as hellish.

A 3-part series on one participant's high dose psilocybin experience in the Pharmacokinetics of Psilocybin in Normal Adult Volunteers study at the University of Wisconsin.

In underground sessions, you’re taking a huge risk choosing to work with someone who may not have adequately prepared or may have dubious subconscious motivations.

What is neurogenesis? Do psychedelics really cause it? If they do, what doors might that open up?